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1st week: PPI (standard dose) and amoxicillin 1 g bid 2nd week: PPI (standard dose), amoxicillin 1 g, metronidazole 0.5 g and clarithromycin 0.5 g bid First line therapy Bismuth-containing quadruple therapy 10–14 PPI (standard dose) bid, tetracycline 0.5 g qid, metronidazole 0.25 g qid and bismuth standard dose qid First line or second line ...
About 60% of the metronidazole is metabolized by oxidation to the main metabolite hydroxymetronidazole and a carboxylic acid derivative, and by glucuronidation. The metabolites show antibiotic and antiprotozoal activity in vitro. [62] Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the ...
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.
metronidazole 500–750 mg three times a day for 5–10 days; tinidazole 2g once a day for 3 days is an alternative to metronidazole; Doses for children are calculated by body weight and a pharmacist should be consulted for help.
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
Metronidazole (for vaginitis caused by Trichomonas) Tinidazole (for intestinal infections caused by Giardia lamblia) Miltefosine (for the treatment of visceral and cutaneous leishmaniasis, currently undergoing investigation for Chagas disease)
Administering a vaginal cream using an applicator. Administering a vaginal tablet without an applicator. Intravaginal administration is a route of administration where the substance is applied inside the vagina.
For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. [2] It is taken by mouth. [1] Diloxanide generally has mild side effects. [3] Side effects may include flatulence, vomiting, and itchiness. [1] During pregnancy it is recommended that it be taken after the first trimester. [1]