Search results
Results from the WOW.Com Content Network
Dexmedetomidine, sold under the brand name Precedex among others, is a medication used for sedation. [4] Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. [10] [11] It is also used in humans to treat acute agitation associated with schizophrenia or bipolar disorder. [5]
Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.
Aripiprazole (Abilify) – atypical antipsychotic (non-selective monoamine receptor modulator) [1]; Bupropion/dextromethorphan (AXS-05; Auvelity) – sigma σ 1 receptor agonist, serotonin reuptake inhibitor, norepinephrine and dopamine reuptake inhibitor, nicotinic acetylcholine receptor negative allosteric modulator, ionotropic glutamate NMDA receptor antagonist, other actions, and CYP2D6 ...
[1] The tetracyclic antidepressants mianserin and mirtazapine are α 2 blockers, although their efficacy as antidepressants may come from their activity at other receptor sites. [citation needed] Mechanistically, α 2 blockers increase adrenergic, dopaminergic and serotonergic neurotransmitters and induce insulin secretion, decreasing blood ...
Detomidine is a sedative with analgesic properties. [3] α 2-adrenergic receptor agonists produce dose-dependent sedative and analgesic effects, mediated by activation of α 2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters.
Atipamezole is a competitive antagonist at ɑ 2-adrenergic receptors that competes with dexmedetomidine, an ɑ 2-adrenergic receptors agonist. It does not directly interact with dexmedetomidine; [ 34 ] rather, their structural similarity allows atipamezole to easily compete for receptor binding sites.
o 2, o 2 both eyes "O 2" usually means oxygen or oxygen therapy: o.d. omni die: every day (once daily) (preferred to "qd" in the UK [10]) o.d. oculus dexter: right eye o can be mistaken as an a which could read "a.d.", meaning right ear, confusion with "omni die" o.m. omni mane: every morning omn. bih. omni bihora: every 2 hours omn. hor. omni ...
Alpha 2 receptors are associated with sympatholytic properties. Alpha-adrenergic agonists have the opposite function of alpha blockers . Alpha adrenoreceptor ligands mimic the action of epinephrine and norepinephrine signaling in the heart, smooth muscle and central nervous system, with norepinephrine being the highest affinity.