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Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
The Summary. Kratom, sometimes referred to as “gas station heroin,” is an herb with opioid- and stimulant-like effects. It can be fatal in very high doses but is not subject to much federal ...
The earliest archaeological evidence of fermentation consists of 13,000-year-old residues of a beer with the consistency of gruel, used by the semi-nomadic Natufians for ritual feasting, at the Raqefet Cave in the Carmel Mountains near Haifa in Israel. [97] [98] Chicha: Yeast byproduct: Corn (Zea mays), fermented Alcohol: Depressant
This is sponsored content. Us Weekly is not endorsing the websites or products set forth below. The use of THC in any capacity may lead to health concerns and users should consult medical ...
(+)-Desmetramadol is a G-protein biased μ-opioid receptor full agonist. [5] It shows comparatively far lower affinity for the δ-and κ-opioid receptors. [6] The two enantiomers of desmetramadol show quite distinct pharmacological profiles; [7] both (+) and (−)-desmetramadol are inactive as serotonin reuptake inhibitors, [8] but (−)-desmetramadol retains activity as a norepinephrine ...
Canada Flag Coat of arms Motto: A mari usque ad mare (Latin) "From Sea to Sea" Anthem: "O Canada" Royal anthem: "God Save the King" Capital Ottawa 45°24′N 75°40′W / 45.400°N 75.667°W / 45.400; -75.667 Largest city Toronto Official languages English French Demonym(s) Canadian Government Federal parliamentary constitutional monarchy • Monarch Charles III • Governor ...
Political map of Canada ar.png; File:Political map of Canada_ms.svg: File:Political map of Canada.svg is a vector version of this file. It should be used in place of ...