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Quinine has not been shown to reduce the duration (length) of a muscle cramp. [6] Quinine treatment may lead to haematologic and cardiac toxicity. Due to its low effectiveness and negative side effects, its use as a medication for treating muscle cramps is not recommended by the FDA. [26] Magnesium is commonly used to treat muscle cramps.
The FDA is also cautioning consumers about off-label use of quinine to treat leg cramps. [19] [20] Quinine is approved for treatment of malaria, but was also commonly prescribed to treat leg cramps and similar conditions. Because malaria is life-threatening, the risks associated with quinine use are considered acceptable when used to treat that ...
“The most common reason for toe cramps is lack of hydration,” says Bradley Schaeffer, DPM, a board-certified podiatrist and foot surgeon at Central Park SOLE and star of TLC’s My Feet Are ...
Muscle cramps, also known as muscle spasms or charley horses, are the involuntary contraction of muscle fibers, says Dr. Lucas Buchler, a physician of sports medicine and orthopaedic surgery at ...
Until about 2010, [11] quinine was often recommended as a relief for leg cramps, although medical research suggested some care was needed in monitoring doses. [12] Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps. [13]
The active ingredient, diclofenac sodium, is a nonsteroidal anti-inflammatory drug (NSAID) that temporarily blocks the production of pain-signaling chemicals called prostaglandins, treating pain ...
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