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In the early stages of placental abruption, there may be no symptoms. [1] When symptoms develop, they tend to develop suddenly. Common symptoms include: sudden-onset abdominal pain [5] [8] contractions that seem continuous and do not stop [5] vaginal bleeding [5] [8] enlarged uterus (disproportionate to the gestational age of the fetus) [5]
Intrauterine hypoxia can be attributed to maternal, placental, or fetal conditions. [12] Kingdom and Kaufmann classifies three categories for the origin of fetal hypoxia: 1) pre-placental (both mother and fetus are hypoxic), 2) utero-placental (mother is normal but placenta and fetus is hypoxic), 3) post-placental (only fetus is hypoxic).
The definitive treatment for pre-eclampsia is the delivery of the baby and placenta, but danger to the mother persists after delivery, and full recovery can take days or weeks. [13] The timing of delivery should balance the desire for optimal outcomes for the baby while reducing risks for the mother. [ 15 ]
Early stillbirth is between 20 and 27 weeks gestation, while late stillbirth is between 28 and 36 weeks gestation. A term stillbirth is when the fetus dies 37 weeks and above. [47] This phenomenon can go beyond grief and can lead to worries about strange maternal feelings or postpartum treatment regarding complications of childbirth. [48]
Especially when these symptoms are evident at early stages of pregnancy. [3] The abnormal invasion of the trophoblast cells, lack of important growth factors such as vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), has an association with the onset of placental disease. [11]
Histopathology of placenta with increased syncytial knotting of chorionic villi, with two knots pointed out. The following characteristics of placentas have been said to be associated with placental insufficiency, however all of them occur in normal healthy placentas and full term healthy births, so none of them can be used to accurately diagnose placental insufficiency: [citation needed]
It begins between the 4 and 8 weeks of pregnancy and usually subsides by 14 to 16 weeks. The exact cause of nausea is not fully understood but it correlates with the rise in the levels of human chorionic gonadotropin , progesterone , and the resulting relaxation of smooth muscle of the stomach.
Ectopic pregnancy is a complication of pregnancy in which the embryo attaches outside the uterus. [5] Signs and symptoms classically include abdominal pain and vaginal bleeding, but fewer than 50 percent of affected women have both of these symptoms. [1]