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  2. Sirtuin 4 - Wikipedia

    en.wikipedia.org/wiki/Sirtuin_4

    SIRT4 is a mitochondrial ADP-ribosyltransferase that inhibits mitochondrial glutamate dehydrogenase 1 activity, thereby downregulating insulin secretion in response to amino acids. [7] A deacetylation of malonyl-CoA decarboxylase enzyme by SIRT4 represses the enzyme activity, inhibiting fatty acid oxidation in muscle and liver cells.

  3. Glutamate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Glutamate_dehydrogenase

    In bacteria, the ammonia is assimilated to amino acids via glutamate and aminotransferases. [2] In plants, the enzyme can work in either direction depending on environment and stress. [ 3 ] [ 4 ] Transgenic plants expressing microbial GLDHs are improved in tolerance to herbicide, water deficit, and pathogen infections. [ 5 ]

  4. Tetrahydrobiopterin - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrobiopterin

    Tetrahydrobiopterin (BH 4, THB), also known as sapropterin (INN), [5] [6] is a cofactor of the three aromatic amino acid hydroxylase enzymes, [7] used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the ...

  5. Antimicrobial peptides - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_peptides

    Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, [1] enveloped viruses, fungi and even transformed or cancerous cells. [2] Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes , can form transmembrane channels , and may ...

  6. MLB to test robo-ump challenge system at spring training ...

    www.aol.com/sports/mlb-test-robo-ump-challenge...

    MLB has experimented with ABS systems in two formats in the minor leagues going back to 2019. Some games have seen the robo umps used to call every pitch, while others have used the challenge ...

  7. DOGE tracker: A running list of what Elon Musk and Vivek ...

    www.aol.com/doge-tracker-running-list-elon...

    Elon Musk and Vivek Ramaswamy aim to cut $2 trillion from the federal budget by July 4, 2026. They've said they'll fire federal employees, "delete" agencies, and publicize all of their work.

  8. Tetrahydrofolic acid - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrofolic_acid

    Tetrahydrofolic acid is a cofactor in many reactions, especially in the synthesis (or anabolism) of amino acids and nucleic acids.In addition, it serves as a carrier molecule for single-carbon moieties, that is, groups containing one carbon atom e.g. methyl, methylene, methenyl, formyl, or formimino.

  9. Kansas leads, Tennessee surges in USA TODAY Sports men's ...

    www.aol.com/kansas-leads-tennessee-surges-usa...

    The top of the USA TODAY Sports men's basketball poll stayed the same but the were plenty of movement in the top 10, led by Tennessee and Kentucky.