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The Nipah virus structural model, constructed at an atomic resolution, depicts a particle with a diameter of 90 nm, adorned with spikes. This model affords a glimpse into the virus's interior. The Nipah virus is known for its high mortality rate and is viewed as a potential candidate for the next pandemic.
The initial case in human outbreaks of Nipah virus has always been zoonotic [8] from exposure to contaminated secretions or tissues of infected bats or pigs. Subsequent human-to-human transmission of Nipah virus occurs via close contact with NiV-infected persons or exposure to NiV-infected body fluids (e.g., blood, urine, nasal secretions). [1]
The 1998–1999 Malaysia Nipah virus outbreak occurred from September 1998 to May 1999 in the states of Perak, Negeri Sembilan and Selangor in Malaysia. A total of 265 cases of acute encephalitis with 105 deaths caused by the virus were reported in the three states throughout the outbreak. [ 1 ]
Nipah and other henipaviral diseases. Nipah is a henipavirus, the most lethal of paramyxoviruses. It was first identified in pigs in Malaysia and Singapore in the late 1980s, though its natural ...
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The index case of the outbreak was reported at a private hospital in Kozhikode district on 5 September, when a 12-year-old boy from Chathamangalam died after testing positive for Nipah virus infection. [49] [50] The new Nipah infection, which spreads through the saliva of fruit bats, came three years after a previous outbreak which claimed 17 ...
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Nipah henipavirus Henipavirus is a genus of negative-strand RNA viruses in the family Paramyxoviridae , order Mononegavirales containing six established species, [ 1 ] [ 2 ] and numerous others still under study. [ 3 ]