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If progesterone is taken by mouth or at high doses, certain central side effects including sedation, sleepiness, and cognitive impairment can also occur. [ 28 ] [ 20 ] The medication is a naturally occurring progestogen and hence is an agonist of the progesterone receptor (PR), the biological target of progestogens like endogenous progesterone ...
At high doses, progestogens can cause low sex hormone levels and associated side effects like sexual dysfunction and an increased risk of bone fractures. [ 3 ] Progestogens are agonists of the progesterone receptors (PRs) and produce progestogenic , or progestational , effects. [ 1 ]
Proponents of bioidentical hormone therapy believe that progesterone offers fewer side effects and improved quality of life compared to MPA. [61] The evidence for this view has been questioned; MPA is better absorbed when taken by mouth, with a much longer elimination half-life leading to more stable blood levels [ 62 ] though it may lead to ...
Other side effects associated with low-dose COCPs are leukorrhea (increased vaginal secretions), reductions in menstrual flow, mastalgia (breast tenderness), and decrease in acne. Side effects associated with older high-dose COCPs include nausea , vomiting , increases in blood pressure , and melasma (facial skin discoloration); these effects ...
Side effects of NETA include menstrual irregularities, headaches, nausea, breast tenderness, mood changes, acne, increased hair growth, and others. [6] NETA is a progestin, or a synthetic progestogen , and hence is an agonist of the progesterone receptor , the biological target of progestogens like progesterone . [ 1 ]
Autoimmune progesterone dermatitis is a rare condition that can occur when progesterone rises during a woman's menstrual cycle. It can cause a physical reaction that may present differently ...
The main drawback of modern HDE for prostate cancer is a high incidence of gynecomastia of about 40 to 77%, although it is generally only mildly or modestly discomforting. [54] In addition, prophylactic irradiation of the breasts can be used to prevent it and has minimal side effects, mostly consisting of temporary skin discoloration. [54]
Conversely, “with too much testosterone, women often have acne, too much hair on the body, hair loss on the head, high blood pressure, elevated cholesterol, skipped cycles, or problems ...
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