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Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB. The medical standard for active TB is a short course treatment involving a combination of isoniazid , rifampicin (also known as Rifampin), pyrazinamide , and ethambutol for the first two months.
Peritoneal tuberculosis: Peritoneal tuberculosis most often presents as abdominal pain and ascites. It can occur most commonly following re-activation of a latent focus of tuberculosis. [3] Intestinal tuberculosis: Tuberculosis of the intestine can affect multiple areas of the bowel simultaneously. The bacilli penetrate the mucosa, cause ...
Aspergilloma in an old tuberculosis cavity; healed, calcified tuberculous lesions are also present towards the right of the image Healed tuberculous cavity, where the entire left lung is destroyed. Post-tuberculosis lung disease (PTLD) is ongoing lung disease that is caused by tuberculosis (TB) but persists after the infection is cured. [1]
This severe form of TB disease, most common in young children and those with HIV, is called miliary tuberculosis. [97] People with this disseminated TB have a high fatality rate even with treatment (about 30%). [53] [98] In many people, the infection waxes and wanes. Tissue destruction and necrosis are often balanced by healing and fibrosis. [94]
Asymptomatic elevation of serum liver enzyme concentrations occurs in 10% to 20% of people taking INH, and liver enzyme concentrations usually return to normal even when treatment is continued. [27] Isoniazid has a boxed warning for severe and sometimes fatal hepatitis, which is age-dependent at a rate of 0.3% in people 21 to 35 years old and ...
Ethionamide is an antibiotic used to treat tuberculosis. [2] Specifically it is used, along with other antituberculosis medications, to treat active multidrug-resistant tuberculosis. [2] It is no longer recommended for leprosy. [3] [2] It is taken by mouth. [2] Ethionamide has a high rate of side effects. [4]
Rifampicin is used for the treatment of tuberculosis in combination with other antibiotics, such as pyrazinamide, isoniazid, and ethambutol. [10] For the treatment of tuberculosis, it is administered daily for at least six months. [11] Combination therapy is used to prevent the development of resistance and to shorten the length of treatment. [12]
(S,S)-(+)-Ethambutol is powerful and selective antitubercular drug.It is a typical example of an old drug that was introduced for clinical use in its unichiral form. . Ethambutol contains two constitutionally symmetrical chiral centers in its structure and exists in three stereoisomeric forms, the enantiomeric pair (+)-(S,S)- and (−)-(R,R)-ethambutol, along with the achiral stereoisomer called m
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