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The main limitation for the monoamine hypothesis of depression is the therapeutic lag between initiation of antidepressant treatment and perceived improvement of symptoms. One explanation for this therapeutic lag is that the initial increase in synaptic serotonin is only temporary, as firing of serotonergic neurons in the dorsal raphe adapt via ...
The metaphysis (pl.: metaphyses) is the neck portion of a long bone between the epiphysis and the diaphysis. [1] It contains the growth plate , the part of the bone that grows during childhood, and as it grows it ossifies near the diaphysis and the epiphyses.
[3] [4] Between the epiphysis and diaphysis (the long midsection of the long bone) lies the metaphysis, including the epiphyseal plate (growth plate). During formation of the secondary ossification center, vascular canals (epiphysial canals) stemming from the perichondrium invade the epiphysis, supplying nutrients to the developing secondary ...
In the United States and Canada, the costs associated with major depression are comparable to those related to heart disease, diabetes, and back problems and are greater than the costs of hypertension. [5] According to the Nordic Journal of Psychiatry, there is a direct correlation between a major depressive episode and unemployment. [6]
At the end of the formation of the secondary ossification center, the only two areas where the cartilage remains is at the articular cartilage covering the epiphysis and at the epiphyseal plate between the epiphysis and diaphysis. [3] A schematic for long bone endochondral ossification: [4]
There’s a difference between being totally over your day and sundowning. In addition to the symptoms listed above, sundowning can include verbal or even physical outbursts, Elhelou says ...
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
"The big distinction is that depression is considered a psychiatric disorder, and burnout is the result of workplace conditions that have psychological symptoms associated with it," says Sarkis.
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