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Most paragangliomas are asymptomatic, present as a painless mass, or create symptoms such as hypertension, tachycardia, headache, and palpitations. [3] While all contain neurosecretory granules, only in 1–3% of cases is secretion of hormones such as catecholamines abundant enough to be clinically significant; in that case manifestations often resemble those of pheochromocytomas (intra ...
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An additional benefit of the DOTA analogues is the ability for treatment with peptide receptor radionuclide therapy, which will be discussed in the treatment section below. [98] Also, HED-PET has shown to be an accurate tool to diagnose and rule out pheochromocytoma in complex clinical scenarios and to characterise equivocal adrenal tumours. [99]
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Hoda Kotb surprised viewers by announcing her upcoming exit from the Today show after 17 years on Thursday, September 26, and behind-the-scenes chatter about her replacement has already begun.
The show played a clip of Gere's role on "The Agency," a political thriller. Once the clip stops playing, Gere raises his middle finger and Guthrie tries to cover it with the papers she's holding ...
Jessica DeCristofaro was diagnosed with stage 4B Hodgkin’s lymphoma, a rare form of cancer, at 28 years old. Here, she shares her story and what doctors missed.
Mutations in the genes encoding alpha subunits of hypoxia-inducible factors (HIF-alpha) have not previously been identified in any cancer. [4]In the Pacak–Zhuang syndrome, patients have somatic gain of function mutations in the genes encoding for HIF2A, leading to prolonged HIF-2α activity and, thus, an increase in its half-life. [5]