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Dimenhydrinate (then known as Compound 1694) was being tested as a potential treatment for hay fever and hives at Johns Hopkins Hospital in 1947 by allergists Dr. Leslie Gay and Dr. Paul Carliner. Among those who received the drug was a pregnant woman who had suffered from motion sickness her entire life.
Doses and Warnings. Sedation and Motion Sickness Before a Car Ride. ... (dimenhydrinate). It is related to Benadryl, and the dose is about the same, 2–4 mg per kilogram of body weight. There is ...
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative.It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.
"Treatment of vertigo due to acute unilateral vestibular loss with a fixed combination of cinnarizine and dimenhydrinate: a double-blind, randomized, parallel-group clinical study". Clin Ther . 26 (6): 866– 77.
In 2000, shortly before the FDA approved the two-drug abortion regimen, Searle – which was by then a subsidiary of Pfizer – wrote a letter to doctors warning them against administering the ...
The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989 by a group led by pharmacologist David Bailey.Their first published clinical report on grapefruit drug interactions was in 1991. [9]
"Hearst Magazines and Yahoo may earn commission or revenue on some items through the links below." Anti-motion sickness glasses are trending on TikTok, with many users claiming that they help ...
Orphenadrine (sold under many brand names) [1] is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine.It is a muscle relaxant that is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs.