Search results
Results from the WOW.Com Content Network
Components that are essential for osteoblast bone formation include mesenchymal stem cells (osteoblast precursor) and blood vessels that supply oxygen and nutrients for bone formation. Bone is a highly vascular tissue, and active formation of blood vessel cells, also from mesenchymal stem cells, is essential to support the metabolic activity of ...
Osteoblasts are generally present on the outer layer of bone, just beneath the periosteum. Attachment of the osteoclast to the osteon begins the process. The osteoclast then induces an infolding of its cell membrane and secretes collagenase and other enzymes important in the resorption process.
The scleral ring or sclerotic ring is a hardened ring of plates, often derived from bone, that is found in the eyes of many animals in several groups of vertebrates. Some species of mammals, amphibians, and crocodilians lack scleral rings. [1] The ring is in the fibrous outer layer of the eye, called the sclera.
Bone is broken down by osteoclasts, and rebuilt by osteoblasts, both of which communicate through cytokine (TGF-β, IGF) signalling. Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts. It is synonymous with bone tissue formation. [1]
During bone formation, an osteoblast is left behind and buried in the bone matrix as an "osteoid osteocyte", which maintains contact with other osteoblasts through extended cellular processes. [9] Although recently it was shown that vascular smooth muscle cells drive osteocyte differentiation [ 10 ] , most aspects of osteocytogenesis remain ...
Via different signalling molecules and combinations the osteochondroprogenitor will differentiate into either osteoblasts or chondrocytes. Simplified diagram of MSCs, and their differentiation pathways into osteoblast and chodrocytic cell lineages. Data based on a 10.5-day-old mouse embryo. Included are the multiple factors for differentiation. [2]
These osteoblasts are responsible for increasing the width of a long bone (the length of a long bone is controlled by the epiphyseal plate) and the overall size of the other bone types. After a bone fracture, the progenitor cells develop into osteoblasts and chondroblasts, which are essential to the healing process. The outer fibrous layer and ...
When symptoms do occur, they may be confused with those of arthritis or other disorders, and so diagnosis may be delayed. Paget's may first be noticed as an increasing deformity of a person's bones. [9] Paget's disease affecting the skull may cause frontal bossing, increased hat size, and headaches.