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Typhoid fever, also known simply as typhoid, is a disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella typhi. [2] [3] Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. [4] [5] Often there is a gradual onset of a high fever over several days. [4]
The American Public Health Association recommends treatment based upon clinical findings and before culturing confirms the diagnosis. [18] Without treatment, death may occur in 10% to 60% of people with epidemic typhus, with people over age 50 having the highest risk of death. [19] In the antibiotic era, death is uncommon if doxycycline is given.
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. [5] This includes use as an eye ointment to treat conjunctivitis. [6] By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. [5]
For over a century, public water systems have used chemical compounds to kill pathogens that cause waterborne diseases such as cholera and typhoid fever, saving countless lives. This purification ...
Symptoms usually begin 6–30 days after exposure and are the same as those of typhoid fever. [1] [3] Often, a gradual onset of a high fever occurs over several days. [1] Weakness, loss of appetite, and headaches also commonly occur. [1] Some people develop a skin rash with rose-colored spots. [2] Without treatment, symptoms may last weeks or ...
Typhoid vaccines are vaccines that prevent typhoid fever. [1] [2] [3] Several types are widely available: typhoid conjugate vaccine (TCV), Ty21a (a live oral vaccine) and Vi capsular polysaccharide vaccine (ViPS) (an injectable subunit vaccine). They are about 30 to 70% effective in the first two years, depending on the specific vaccine in ...
She was detained and quarantined after another typhoid outbreak. She died of pneumonia in 1938, after 26 years in quarantine. [32] [33] A well-publicised outbreak occurred in Croydon, Surrey, now part of London, in 1937. [34] It resulted in 341 cases of typhoid (43 fatal), [35] [36] and it caused considerable local discontent.
The Vi capsular polysaccharide vaccine (or ViCPS) is a typhoid vaccine recommended by the World Health Organization for the prevention of typhoid (another is Ty21a).The vaccine was first licensed in the US in 1994 and is made from the purified Vi capsular polysaccharide from the Ty2 Salmonella Typhi strain; it is a subunit vaccine.
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