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The most common source of ethylene glycol is automotive antifreeze or radiator coolant, where concentrations are high. [9] Other sources of ethylene glycol include windshield deicing agents, brake fluid, motor oil, developing solutions for hobby photographers, wood stains, solvents, and paints. [9]
Ethylene glycol, antifreeze, is extremely toxic to dogs. It has a sweet taste and thus dogs will drink it. As little as 2 1/2 tablespoons can kill a medium-sized dog in 2–3 days. This type of poisoning is often fatal as dog owners do not know their pet has ingested the antifreeze. De-icing fluids can also contain ethylene glycol.
Fomepizole is used to treat ethylene glycol and methanol poisoning. It acts to inhibit the breakdown of these toxins into their active toxic metabolites. Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase, [6] found in the liver. This enzyme plays a key role in the metabolism of ethylene glycol, and of methanol.
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Treatment needs to be within eight hours of ingestion to be successful. [174] See Ethylene glycol poisoning. Mouse and rat poison* ingestion is common in dogs. Most rodenticides in the United States are anticoagulant by depleting vitamin K. This type is the most frequent cause of poisoning in pets.
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Visible symptoms of arsenic poisoning following exposure. Poisoning is the harmful effect which occurs when toxic substances are introduced into the body. [1] The term "poisoning" is a derivative of poison, a term describing any chemical substance that may harm or kill a living organism upon ingestion. [2]
Burton adds, “It’s also an excellent choice for dogs prone to jumping – after all, they can’t jump and eat from the ground simultaneously!” 3. Tossed away from you