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  2. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    The Glomerular filtration rate (GFR) is regarded as the best overall measure of the kidney's ability to carry out these numerous functions. An estimate of the GFR is used clinically to determine the degree of kidney impairment and to track the progression of the disease. The GFR, however, does not reveal the source of the kidney disease.

  3. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).

  4. Andrew S. Levey - Wikipedia

    en.wikipedia.org/wiki/Andrew_S._Levey

    Levey is known for developing the most widely used equations to estimate GFR (renal function) globally.He pioneered work with the MDRD Study Equation, [1] led the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), which pooled measured kidney function CKD data from studies all over the world to develop equations to estimate kidney function from serum creatinine, cystatin C, and ...

  5. MDCalc - Wikipedia

    en.wikipedia.org/wiki/MDCalc

    MDCalc is a free online medical reference for healthcare professionals that provides point-of-care clinical decision-support tools, including medical calculators, scoring systems, and algorithms. [1] MDCalc is also a mobile and web app. [ 2 ] The decision-support tools are based on published clinical research, [ 3 ] and MDCalc’s content is ...

  6. Fractional excretion of sodium - Wikipedia

    en.wikipedia.org/wiki/Fractional_excretion_of_sodium

    This is the numerator in the equation. The denominator is the total amount of sodium filtered by the kidneys. This is calculated by multiplying the plasma sodium concentration by the glomerular filtration rate (GFR) calculated using creatinine filtration. The flow rates then cancel out, simplifying to the standard equation: [1]

  7. Creatinine - Wikipedia

    en.wikipedia.org/wiki/Creatinine

    Algorithms to estimate GFR from creatinine concentration and other parameters are discussed in the renal function article. Unfortunately, the MDRD Study equation was developed in people with chronic kidney disease, and its major limitations are imprecision and systematic underestimation of measured GFR (bias) at higher/normal values. [20]

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  9. Renal clearance ratio - Wikipedia

    en.wikipedia.org/wiki/Renal_clearance_ratio

    C x is the renal plasma clearance of X C in is the renal plasma clearance of inulin . Creatinine is sometimes used instead of inulin as the reference substance; for example, the calcium-creatinine clearance ratio is used in an attempt to distinguish between different causes of a high plasma calcium concentration. [ 3 ]

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