Ads
related to: what is bromocriptine prescribed forgoodrx.com has been visited by 100K+ users in the past month
Working to be "the most powerful patient advocate in America" - Forbes
Search results
Results from the WOW.Com Content Network
Bromocriptine, originally marketed as Parlodel and subsequently under many brand names, [1] is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and, as an adjunct, type 2 diabetes.
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS) and are implicated in many neurological processes, including motivational and incentive salience, cognition, memory, learning, and fine motor control, as well as modulation of neuroendocrine signaling.
Bromocriptine is a D 2 receptor agonist and D 1 receptor antagonist with a binding affinity to D 2 receptors of anterior pituitary cells, exclusively on lactotrophs. Bromocriptine stimulates Na +, K +-ATPase activity and/or cytosolic Ca 2+ elevation and therefore reduction of prolactin which leads to no production of cAMP.
Vagus nerve stimulation therapy improved the symptoms of treatment-resistant depression for nearly 500 participants in a major clinical trial.
Cabergoline is frequently used as a first-line agent in the management of prolactinomas due to its higher affinity for D 2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine, though in pregnancy bromocriptine is often still chosen since there is less data on safety in pregnancy for ...
Ergotamine interacts with serotonin, adrenergic, and dopamine receptors. [17] [18] It is an agonist of serotonin receptors including the 5-HT 1 and 5-HT 2 subtypes. [17]Ergotamine is an agonist of the serotonin 5-HT 2B receptor and has been associated with cardiac valvulopathy. [19]