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  2. Nucleophilic aromatic substitution - Wikipedia

    en.wikipedia.org/wiki/Nucleophilic_aromatic...

    By the same coin, the loss of the chloride or hydroxide is fast, because the ring regains aromaticity. Recent work indicates that, sometimes, the Meisenheimer complex is not always a true intermediate but may be the transition state of a 'frontside S N 2' process, particularly if stabilization by electron-withdrawing groups is not very strong. [2]

  3. Substitution reaction - Wikipedia

    en.wikipedia.org/wiki/Substitution_reaction

    Coupling reactions are a class of metal-catalyzed reactions involving an organometallic compound RM and an organic halide R′X that together react to form a compound of the type R-R′ with formation of a new carbon–carbon bond. Examples include the Heck reaction, Ullmann reaction, and Wurtz–Fittig reaction. Many variations exist. [3]

  4. Associative substitution - Wikipedia

    en.wikipedia.org/wiki/Associative_substitution

    The terminology is typically applied to organometallic and coordination complexes, but resembles the Sn2 mechanism in organic chemistry. The opposite pathway is dissociative substitution, being analogous to the Sn1 pathway. Intermediate pathways exist between the pure associative and pure dissociative pathways, these are called interchange ...

  5. SN1 reaction - Wikipedia

    en.wikipedia.org/wiki/SN1_reaction

    In this regime, the first step (ionization of the alkyl bromide) is slow, rate-determining, and irreversible, while the second step (nucleophilic addition) is fast and kinetically invisible. However, under certain conditions, non-first-order reaction kinetics can be observed.

  6. SN2 reaction - Wikipedia

    en.wikipedia.org/wiki/SN2_reaction

    Competition experiment between SN2 and E2. With ethyl bromide, the reaction product is predominantly the substitution product. As steric hindrance around the electrophilic center increases, as with isobutyl bromide, substitution is disfavored and elimination is the predominant reaction. Other factors favoring elimination are the strength of the ...

  7. Metal detector - Wikipedia

    en.wikipedia.org/wiki/Metal_detector

    A metal detector is an instrument that detects the nearby presence of metal. Metal detectors are useful for finding metal objects on the surface, underground, and under water. A metal detector consists of a control box, an adjustable shaft, and a variable-shaped pickup coil.

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