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  2. Congenital insensitivity to pain - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    A patient and doctor discuss congenital insensitivity to pain. For people with this disorder, cognition and sensation are otherwise normal; for instance, patients can still feel discriminative touch (though not always temperature [3]), and there are generally no detectable physical abnormalities.

  3. Congenital insensitivity to pain with anhidrosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_insensitivity...

    Since people with this condition are unable to sweat, they are unable to properly regulate their body temperature. [1] Those affected are unable to feel pain and temperature. [2] [3] The absence of pain experienced by people with CIPA puts them at high risk for accidental self-injury. Corneal ulceration occurs due to lack of protective impulses ...

  4. Pain tolerance - Wikipedia

    en.wikipedia.org/wiki/Pain_tolerance

    First is the biological component—the headache or skin prickling that activates pain receptors. Second is the brain’s perception of pain—how much focus is spent paying attention to or ignoring the pain. [2] The brain’s perception of pain is a response to signals from pain receptors that sensed the pain in the first place.

  5. 8 surprising ways your brain powers the rest of your body - AOL

    www.aol.com/lifestyle/8-surprising-ways-brain...

    But the brain itself has no pain receptors. That headache pain is coming from nerves somewhere else in your head. This is why patients can sometimes be awake during brain surgery, as a surgeon ...

  6. Nociceptor - Wikipedia

    en.wikipedia.org/wiki/Nociceptor

    ' pain receptor ') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1] [2] [3] to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this process is called nociception.

  7. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    Afferent pain-receptive nerves, those that bring signals to the brain, comprise at least two kinds of fibers - a fast, relatively thick, myelinated "Aδ" fiber that carries messages quickly with intense pain, and a small, unmyelinated, slow "C" fiber that carries the longer-term throbbing and chronic pain. Large-diameter Aβ fibers are ...

  8. Menopause: 6 surprising symptoms you didn't know about - AOL

    www.aol.com/lifestyle/menopause-6-surprising...

    Nonhormonal treatments: For people who aren't interested in taking hormones or who can't — for instance, breast cancer patients whose treatments and risk factors preclude hormone therapy ...

  9. Mechanosensation - Wikipedia

    en.wikipedia.org/wiki/Mechanosensation

    Aδ fibers are characterized by thin axons and thin myelin sheaths, and are either D-hair receptors or nociceptive neurons. Aδ fibers conduct at a rate of up to 25 m/s. D-hair receptors have large receptive fields and very low mechanical thresholds, and have been shown to be the most sensitive of known cutaneous mechanoreceptors.