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The underlying cause of this type of bronchoconstriction appear to be the large volume of cool, dry air inhaled during strenuous exercise. The condition appears to improve when the air inhaled is more fully humidified and closer to body temperature. This specific condition, in the general population, can vary between 7 and 20 percent.
Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]
In people with psoriasis using topical steroids it occurs in up to 5% of people after a year of use. [5] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8] Skin atrophy can occur with both prescription and over the counter steroids creams. [9]
[1] [2] It commonly occurs in the winter season in the Northern Hemisphere. [1] It is the leading cause of hospitalizations in those less than one year of age in the United States. [9] [8] The risk of death among those who are admitted to hospital is extremely low at about 1%. [4] Outbreaks of the condition were first described in the 1940s. [10]
About 2-5% of all children will experience such a seizure during their childhood. [26] In most cases, a febrile seizure will not indicate epilepsy. [26] Approximately 40% of children who experience a febrile seizure will have another one. [26] In those with epilepsy, fever can trigger a seizure.
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Once remission is induced, maintenance levels can be used: sulfasalazine 2 g/day, mesalamine 1.2-2.4 g/day, or olsalazine 1 g/day. Patients on high dose sulfasalazine require folic supplementation (1 mg/day) because it inhibits folate absorption. If oral Mesalazine is still not working, prednisone is often given, starting at 40–60 mg/day.
Children affected by allergies in the developed world: [2] 1 in 13 have eczema; 1 in 8 have allergic rhinitis; 3-6% are affected by food allergy; Children in the United States under 18 years of age: [3] Percent with any allergy: 27.2%; Percent with seasonal allergy: 18.9%; Percent with eczema: 10.8%; Percent with food allergy: 5.8%
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