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The main pathways of linezolid metabolism in humans, showing all metabolites that account for >1% of an excreted dose. Legend. PNU-142300, accounts for ~10% of excreted dose at steady state; PNU-142586, accounts for ~45% of excreted dose at steady state; PNU-173558, accounts for ~3.3% of excreted dose at steady state; Date: 15 May 2009: Source
Linezolid is a member of the oxazolidinone class of medications. [10] Linezolid was discovered in the mid-1990s, and was approved for commercial use in 2000. [16] [17] It is on the World Health Organization's List of Essential Medicines. [18] The World Health Organization classifies linezolid as critically important for human medicine. [19]
Skeletal formula of the antibiotic linezolid, highlighting the oxazolidinone pharmacophore (in blue) and desirable structural characteristics (in orange). Created using ACD/ChemSketch 10.0 and Inkscape. Date: 24 June 2009: Source: Own work based on: Brickner SJ (1996).
The following other wikis use this file: Usage on ar.wikipedia.org لينيزوليد; Usage on azb.wikipedia.org لینزولید; Usage on cy.wikipedia.org
Skeletal formulae of the antibiotic linezolid (top) and the anticoagulant rivaroxaban (bottom), highlighting their similar oxazolidinone core (in blue). Created using ACD/ChemSketch 10.0 and Inkscape. Date: 11 June 2009: Source: Own work. The structural similarity between the drugs is discussed in European Medicines Agency (2008).
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Parts-per-million cube of relative abundance by mass of elements in an average adult human body down to 1 ppm. About 99% of the mass of the human body is made up of six elements: oxygen, carbon, hydrogen, nitrogen, calcium, and phosphorus. Only about 0.85% is composed of another five elements: potassium, sulfur, sodium, chlorine, and magnesium ...
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