Search results
Results from the WOW.Com Content Network
A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. [1] It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction. [2] Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy.
The neuromuscular junction (NMJ) is the most well-characterized synapse in that it provides a simple and accessible structure that allows for easy manipulation and observation. The synapse itself is composed of three cells: the motor neuron , the myofiber , and the Schwann cell .
Neuromuscular junction diseases in this category include snake venom poisoning, botulism, arthropod poisoning, organophosphates and hypermagnesemia.(reference 13) Organophosphates are present in many insecticides and herbicides. They are also the basis of many nerve gases.(reference 27) Hypermagnesmia is a condition where the balance of ...
Note the differences in the scales on the X- and Y-axes. Both are taken from recordings at the mouse neuromuscular junction. End plate potentials (EPPs) are the voltages which cause depolarization of skeletal muscle fibers caused by neurotransmitters binding to the postsynaptic membrane in the neuromuscular junction. They are called "end plates ...
Mind Map showing a summary of Neuromuscular depolarizing agent. A depolarizing neuromuscular blocking agent is a form of neuromuscular blocker that depolarizes the motor end plate. [15] An example is succinylcholine. Depolarizing blocking agents work by depolarizing the plasma membrane of the muscle fiber, similar to acetylcholine.
Neuromuscular disease can also be diagnosed by various blood tests and using electrodiagnostic medicine tests [23] including electromyography [24] (measuring electrical activity in muscles) and nerve conduction studies. [25] Genetic testing is an important part of diagnosing inherited neuromuscular conditions. [23]
In biology, a motor unit is made up of a motor neuron and all of the skeletal muscle fibers innervated by the neuron's axon terminals, including the neuromuscular junctions between the neuron and the fibres. [1] Groups of motor units often work together as a motor pool to coordinate the contractions of a single muscle.
MuSK (for Muscle-Specific Kinase) [1] is a receptor tyrosine kinase required for the formation and maintenance of the neuromuscular junction. [2] It is activated by a nerve-derived proteoglycan called agrin, [3] which is similarly also required for neuromuscular junction formation. [4]