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In early development (before birth and during the first few months), the brain undergoes more changes in size, shape and structure than at any other time in life. Improved understanding of cerebral development during this critical period is important for mapping normal growth, and for investigating mechanisms of injury associated with risk ...
Cortical white matter increases from childhood (~9 years) to adolescence (~14 years), most notably in the frontal and parietal cortices. [8] Cortical grey matter development peaks at ~12 years of age in the frontal and parietal cortices, and 14–16 years in the temporal lobes (with the superior temporal cortex being last to mature), peaking at about roughly the same age in both sexes ...
Activity-dependent mechanisms influence neural circuit development and are crucial for laying out early connectivity maps and the continued refinement of synapses which occurs during development. [42] There are two distinct types of neural activity we observe in developing circuits -early spontaneous activity and sensory-evoked activity.
TCF4 is primarily involved in neurological development of the fetus during pregnancy by initiating neural differentiation by binding to DNA. It is found in the central nervous system, somites, and gonadal ridge during early development.
The brain divides into 5 vesicles, including the early telencephalon. Leg buds form and hands form as flat paddles on the arms. Rudimentary blood moves through primitive vessels connecting to the yolk sac and chorionic membranes. The metanephros, precursor of the definitive kidney, starts to develop. The initial stomach differentiation begins. [5]
Spina bifida (SB; /ˌspaɪnə ˈbɪfɪdə/, [9] Latin for 'split spine') [10] is a birth defect in which there is incomplete closing of the spine and the membranes around the spinal cord during early development in pregnancy. [1] There are three main types: spina bifida occulta, meningocele and myelomeningocele. [1]
Stages of neuronal development in the fetal cerebral cortex Model of mammalian neurogenesis [4]. During embryonic development, the mammalian central nervous system (CNS; brain and spinal cord) is derived from the neural tube, which contains NSCs that will later generate neurons. [3]
In human pregnancy, prenatal development is also called antenatal development. The development of the human embryo follows fertilization , and continues as fetal development . By the end of the tenth week of gestational age , the embryo has acquired its basic form and is referred to as a fetus .