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Dapagliflozin is an example of an SGLT-2 inhibitor, it is a competitive, highly selective inhibitor of SGLT. It acts via selective and potent inhibition of SGLT-2, and its activity is based on each patient's underlying blood sugar control and kidney function. The results are decreased kidney reabsorption of glucose, glucosuria effect increases ...
Roy Williams retired after serving as the head coach at North Carolina for 18 seasons. [2] Hubert Davis was hired as the next head coach of North Carolina. [3] Boston College fired Jim Christian in the middle of the season, after leading the team to a 3–13 record. Christian's overall record with Boston College was 78–132 and 26–94 in ACC ...
The regular season began on Saturday August 27, 2022, and will end on Saturday November 26, 2022. The ACC Championship Game will be played on Saturday December 3, 2022, at Bank of America Stadium in Charlotte, North Carolina.
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Heart failure with preserved ejection fraction (HFpEF) is a form of heart failure in which the ejection fraction – the percentage of the volume of blood ejected from the left ventricle with each heartbeat divided by the volume of blood when the left ventricle is maximally filled – is normal, defined as greater than 50%; [1] this may be measured by echocardiography or cardiac catheterization.
2022 ACC men's soccer tournament List of sports-related pages with the same or similar names This article includes a list of sports-related pages with the same or similar names.
[2] [3] SGLT1, encoded by the SLC5A1 gene, is primarily expressed in the late proximal tubule (S3 segment) and accounts for the remaining 3% of glucose reabsorption. [2] [3] In addition to SGLT1 and SGLT2, there are 10 other members in the human protein family SLC5A. [4] SLC5A4, also known as SGLT3, is a member of the sodium-glucose ...
SGLT2 is a member of the sodium glucose cotransporter family, which are sodium-dependent glucose transport proteins. SGLT2 is the major cotransporter involved in glucose reabsorption in the kidney. [6] SGLT2 is located in the early proximal tubule, and is responsible for reabsorption of 80-90% of the glucose filtered by the kidney glomerulus. [7]