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  2. Methicillin-resistant Staphylococcus aureus - Wikipedia

    en.wikipedia.org/wiki/Methicillin-resistant...

    For children with MRSA-infected bone or joints, treatment is individualized and long-term. Neonates can develop neonatal pustulosis as a result of topical infection with MRSA. [4] Clindamycin is not approved for the treatment of MRSA infection, but it is still used in children for soft-tissue infections. [4]

  3. MRSA ST398 - Wikipedia

    en.wikipedia.org/wiki/MRSA_ST398

    Staphylococcus aureus is a gram-positive, spherical bacterium that can cause a range of infections in humans and animals. And Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that is resistant to many antibiotics. The abbreviation "ST" in MRSA ST398 refers to the sequence type of the bacterium.

  4. Vancomycin-resistant Staphylococcus aureus - Wikipedia

    en.wikipedia.org/wiki/Vancomycin-resistant...

    Resistance genes interfere with the normal antibiotic function and allow bacteria to grow in the presence of the antibiotic. [4] Resistance in VRSA is conferred by the plasmid-mediated vanA gene and operon. [5] Although VRSA infections are uncommon, VRSA is often resistant to other types of antibiotics and a potential threat to public health ...

  5. Drug of last resort - Wikipedia

    en.wikipedia.org/wiki/Drug_of_last_resort

    One of the most commonly known examples of both antimicrobial resistance and the relationship to the classification of a drug of last resort is the emergence of Staphylococcus aureus (MRSA) (sometimes also referred to as multiple-drug resistant S. aureus due to resistance to non-penicillin antibiotics that some strains of S. aureus have shown ...

  6. Antimicrobial resistance - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_resistance

    Antibiotic resistance, a significant AMR subset, enables bacteria to survive antibiotic treatment, complicating infection management and treatment options. [3] Resistance arises through spontaneous mutation, horizontal gene transfer , and increased selective pressure from antibiotic overuse, both in medicine and agriculture, which accelerates ...

  7. Persister cells - Wikipedia

    en.wikipedia.org/wiki/Persister_cells

    Hence the residual organisms were not antibiotic resistant mutants but rather a subpopulation of what he called ‘persisters’. [7] The formation of bacterial persisters is now known to be a common phenomenon that can occur by the formation of persister cells prior to the antibiotic treatment [8] or in response to a variety of antibiotics. [9]

  8. Multiple drug resistance - Wikipedia

    en.wikipedia.org/wiki/Multiple_drug_resistance

    The use of bacteriophages (viruses which kill bacteria) is a developing area of possible therapeutic treatments. [20] It is necessary to develop new antibiotics over time since the selection of resistant bacteria cannot be prevented completely. This means with every application of a specific antibiotic, the survival of a few bacteria which ...

  9. Antimicrobial spectrum - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_spectrum

    Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.