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Lens development is closely related to optic vesicle development. The interaction between the growing vesicle and the ectoderm causes the ectoderm to thicken at that point. This thickened portion of the ectoderm is called the lens placode. Next, the placode invaginates and forms a pouch referred to as the lens pit.
The eyes begin to develop as a pair of diverticula (pouches) from the lateral aspects of the forebrain.These diverticula make their appearance before the closure of the anterior end of the neural tube; [1] [2] after the closure of the tube around the 4th week of development, they are known as the optic vesicles.
The lens is located towards the front part of the vertebrate eye, called the anterior segment, which includes the cornea and iris positioned in front of the lens. The lens is held in place by the suspensory ligaments (Zonule of Zinn), [1] attaching the lens at its equator to the rest of the eye [2] [3] through the ciliary body.
During embryonic development of the eye, the outer wall of the bulb of the optic vesicles becomes thickened and invaginated, and the bulb is thus converted into a cup, the optic cup (or ophthalmic cup), consisting of two strata of cells.
(B) Optic vesicles bilaterally protrude from either side of the forebrain approaching the thickened surface ectoderm (lens placodes). (C) The interaction between the optic vesicle and the lens placode of the surface ectoderm results in optic vesicle invagination, optic cup formation and lens placode evagination (lens pit).
The optic vesicles project toward the sides of the head, and the peripheral part of each expands to form a hollow bulb, while the proximal part remains narrow and constitutes the optic stalk. [1] [2] Closure of the choroidal fissure in the optic stalk occurs during the seventh week of development.
Sheep eye lens capsule with ligaments attached. The capsule is lifting off the lens showing cell fiber ends beneath. Microscope image of lens capsule in relation to lens cell types. The lens capsule is a component of the globe of the eye. [1] It is a clear elastic basement membrane similar in composition to other basement membranes in the body.
Vesicle may refer to: In cellular biology or chemistry. Vesicle (biology and chemistry), a supramolecular assembly of lipid molecules, like a cell membrane; Synaptic vesicle; In human embryology. Vesicle (embryology), bulge-like features of the early neural tube during embryonic brain development; Auditory vesicle; Optic vesicles; In human ...