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Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole insecticide class. [3] Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor (IRAC group 2B) and glutamate-gated chloride (GluCl) channels.
Flea infestation in the home is treated in various ways. Insecticides.A spot-on insecticide kills the fleas on the pet. A fogger or spray insecticide containing an insect growth regulator, such as pyriproxyfen or methoprene can kill eggs and pupae, which are quite resistant to insecticides.
Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. [2] It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats.
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The US Food and Drug Administration (FDA) approved it for flea treatment in dogs in May 2014, [17] and approved the combination fluralaner/moxidectin (Bravecto Plus) as a topical treatment for cats in November 2019.
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