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Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. [2] [3] Usually acquired in childhood, it is a leading cause of permanent disability worldwide, impacting over a hundred million people and manifesting itself in a variety of severe clinical pathologies [6] [7] While most cases have no symptoms, some people develop a syndrome called elephantiasis, which ...
Brugia malayi is a filarial (arthropod-borne) nematode (roundworm), one of the three causative agents of lymphatic filariasis in humans. Lymphatic filariasis, also known as elephantiasis, is a condition characterized by swelling of the lower limbs.
Elephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling . [ 1 ] [ 2 ] It is characterised by edema, hypertrophy , and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels ( lymphedema ). [ 2 ]
4 Life cycle of Filarioidea. ... The ones that mainly occupy lymph vessels and cause conditions such as adenolymphangitis, elephantiasis, and filarial fever are:
Its complete its life cycle in two hosts, man being the definitive host while the mosquitoes act as the intermediate host. The most common mosquito vectors that aid in transmission are Anopheles in Africa, Culex in America, Aedes and Mansonia in Asia (Zulfiqar et al., 2023). Female worms are ovoviviparous and can produce thousands of juveniles ...
Wuchereria bancrofti is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis.It is one of the three parasitic worms, together with Brugia malayi and B. timori, that infect the lymphatic system to cause lymphatic filariasis.
Brugia is a genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis. [1] Specifically, of the three species known, Brugia malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats, dogs and other animals.
Patrick Manson discovered the life cycle of elephantiasis, caused by nematode worms transmitted by mosquitoes, in 1877. Manson further predicted that the malaria parasite, Plasmodium, had a mosquito vector, and persuaded Ronald Ross to investigate. Ross confirmed that the prediction was correct in 1897–1898.