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In asymptomatic infections, the amoeba lives by eating and digesting bacteria and food particles in the gut, a part of the gastrointestinal tract. [9] It does not usually come in contact with the intestine itself due to the protective layer of mucus that lines the gut. Disease occurs when amoeba comes in contact with the cells lining the intestine.
Free-living amoebae (or "FLA") [1] are a group of protozoa that are important causes of infectious disease in humans and animals. Naegleria fowleri is often included in the group "free-living amoebae", [2] [3] and this species causes a usually fatal condition traditionally called primary amoebic meningoencephalitis (PAM).
Clockwise from top right: Amoeba proteus, Actinophrys sol, Acanthamoeba sp., Nuclearia thermophila., Euglypha acanthophora, neutrophil ingesting bacteria. An amoeba (/ ə ˈ m iː b ə /; less commonly spelled ameba or amœba; pl.: amoebas (less commonly, amebas) or amoebae (amebae) / ə ˈ m iː b i /), [1] often called an amoeboid, is a type of cell or unicellular organism with the ability ...
For example, Shigella is a longstanding World Health Organization (WHO) target for vaccine development, and sharp declines in age-specific diarrhea/dysentery attack rates for this pathogen indicate that natural immunity does develop following exposure; thus, vaccination to prevent this disease should be feasible. The development of vaccines ...
Naegleria fowleri, also known as the brain-eating amoeba, is a species of the genus Naegleria. It belongs to the phylum Percolozoa and is classified as an amoeboflagellate excavate , [ 1 ] an organism capable of behaving as both an amoeba and a flagellate .
Role of neutrophils in rodent amebic liver abscess [4]. Due to the difficulty of exploring host and amebic factors involved in the pathogenesis of amebic liver abscess in humans, most studies have been conducted with animal models (e.g., mice, gerbils, and hamsters).
Infectious disease Dientamoebiasis is a medical condition caused by infection with Dientamoeba fragilis , a single-cell parasite that infects the lower gastrointestinal tract of humans. It is an important cause of traveler's diarrhea, chronic abdominal pain, chronic fatigue, [ citation needed ] and failure to thrive in children.
Balamuthia mandrillaris is a free-living amoeba that causes the rare but deadly neurological condition granulomatous amoebic encephalitis (GAE). [1] B. mandrillaris is a soil-dwelling amoeba and was first discovered in 1986 in the brain of a mandrill that died in the San Diego Wild Animal Park.