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A myoma is a type of tumor that involves muscle cells. [1] There are two main types of myoma: Leiomyomas which occur in smooth muscle. [1] They most commonly occur as uterine fibroids, but may also form in other locations. Rhabdomyomas which occur in striated muscle. [1] [2] [3] They are rare tumors, occur in childhood and often become malignant.
Leiomyoma enucleated from a uterus. External surface on left; cut surface on right. Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei Immunohistochemistry for β-catenin in uterine leiomyoma, which is negative as there is only staining of cytoplasm ...
Hematological values such as hemoglobin, hematocrit, and red blood cell counts are elevated in patients with myomatous erythrocytosis syndrome. [3]The diagnostic criteria for myomatous erythrocytosis syndrome includes polycythemia, uterine myoma, and return of hemoglobin levels to normal following fibroid excision surgery.
African American women are two to three times more likely to get fibroids than Caucasian women. [12] [13] [74] In African American women fibroids seem to occur at a younger age, grow more quickly, and are more likely to cause symptoms. [75] This leads to higher rates of surgery for African Americans, both myomectomy, and hysterectomy. [76]
Rare, more common in women. Angioleiomyoma ( vascular leiomyoma , angiomyoma ) of the skin is thought to arise from vascular smooth muscle , and is generally acquired . [ 3 ] Angioleiomyomas appear as small (<2 cm), firm, movable, slow growing subcutaneous nodules .
Adenomyoma is a tumor (-oma) including components derived from glands (adeno-) and muscle (-my-). [1] It is a type of complex and mixed tumor, and several variants have been described in the medical literature.
Fibroids (leiomyoma) — fibroids in the wall of the uterus cause increased menstrual loss if they protrude into the central cavity and thereby increase endometrial surface area. Coagulation defects (rare) — with the shedding of an endometrial lining's blood vessels, normal coagulation process must occur to limit and eventually stop the blood ...
A thin arborizing vascular network, a large myxoid stroma, mild to moderate cellularity with spindled to stellate cells with little or mild atypia, and the lack of nuclear pleomorphism or mitotic activity are among the histologic markers that are consistently present in cutaneous myxoma.