Search results
Results from the WOW.Com Content Network
Low to moderate doses of CBD might reduce some of the paranoia, anxiety, [18] and reduction of hippocampal volumes that the current high potency THC marijuana (in the last decades, THC content increased and CBD content decreased) can cause, if the CBD substitutes a part of the THC dose.
The main metabolite in urine is the ester of glucuronic acid and 11-OH-THC and free THC-COOH. In the feces, mainly 11-OH-THC was detected. [36] Estimates of the elimination half-life of THC are variable. [22] THC was reported to have a fast initial half-life of 6 minutes and a long terminal half-life of 22 hours in a population pharmacokinetic ...
In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index, [21] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation. [22]
Behold: 11 THC seltzer options, available in states where cannabis is legal. For specific locations, make sure to check each website’s store locator. Prices and availability are subject to change.
Cannabis concentrate, also called marijuana concentrate, marijuana extract, or cannabis extract, is a tetrahydrocannabinol (THC) and/or cannabidiol (CBD) concentrated mass. Cannabis concentrates contain high THC levels that range from 40% to over 90%, [ 1 ] [ 2 ] stronger in THC content than high-grade marijuana, which normally measures around ...
A man smoking cannabis in Kolkata, India. Cannabis consumption refers to the variety of ways cannabis is consumed, among which inhalation (smoking and vaporizing) and ingestion are most common. All consumption methods involve heating the plant's THCA to decarboxylate it into THC, either at the time of consumption or during preparation. Salves ...
Importantly, 11-OH-THC, the active metabolite generated via first-pass-metabolism of THC, demonstrates different binding profile at TRP channels [13] Potential relevance to sleep induction (e.g., increased adenosine levels [16]) and increased quality of sleep [13] Dose-dependent anxiolytic effects, [13] with anxiogenic effects at high doses
Nabiximols [2] sold under the brand name Sativex, is a specific Cannabis extract that was approved in 2010 as a botanical drug in the United Kingdom. Nabiximols is sold as a mouth spray intended to alleviate neuropathic pain , spasticity , overactive bladder , and other symptoms of multiple sclerosis ; it was developed by the UK company GW ...