Search results
Results from the WOW.Com Content Network
The hemagglutination assay or haemagglutination assay (HA) and the hemagglutination inhibition assay (HI or HAI) were developed in 1941–42 by American virologist George Hirst as methods for quantifying the relative concentration of viruses, bacteria, or antibodies.
Blood compatibility testing is routinely performed before a blood transfusion.The full compatibility testing process involves ABO and RhD (Rh factor) typing; screening for antibodies against other blood group systems; and crossmatching, which involves testing the recipient's blood plasma against the donor's red blood cells as a final check for incompatibility.
The assay produces a result of hemagglutination units (HAU), with typical PFU to HAU ratios in the 10 6 range. [12] [13] [14] This assay takes ~1–2 hours to complete. The hemagglutination inhibition assay is a common variation of the HA assay used to measure flu-specific antibody levels in blood serum.
Hemagglutination, or haemagglutination, is a specific form of agglutination that involves red blood cells (RBCs). It has two common uses in the laboratory: blood typing and the quantification of virus dilutions in a haemagglutination assay .
Hemagglutination assay. Some viruses attach to molecules present on the surface of red blood cells, for example, influenza virus. [10] A consequence of this is that ...
A schematic diagram of the experimental setup to detect hemagglutination for blood typing. Hemagglutination blood typing detection: [24] This method consists of measuring the blood’s reflectance spectrum alone (non-agglutination), and that of blood mixed with antibody reagents (agglutination) using a waveguide-mode sensor. As a result, some ...
There are a number of treponemal-specific tests such as the fluorescent treponemal antibody-absorption test, T. pallidum hemagglutination assays , and the microhemagglutination assay . [citation needed] The MHA-TP is used to confirm a syphilis infection after another method tests positive for the syphilis bacteria.
TPHA is an indirect hemagglutination assay used for the detection and titration of antibodies against the causative agent of syphilis, Treponema pallidum subspecies pallidum. [ citation needed ] In the test, red blood cells ( erythrocytes ) are sensitized with antigens from T. pallidum pallidum .