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Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. [2] It treats and prevents infections of heartworms , fleas , ear mites , sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms , and roundworms in cats.
A comparison of 3 insecticides (selamectin, fipronil, imidacloprid) showed that selamectin reduced larval cat fleas ≥93.5% after 24 h at doses of ≥0.3 μg. In contrast, at 24 h neither fipronil nor imidacloprid reached 90% reduction, even at the highest doses tested (0.5 μg for fipronil and 5.0 μg for imidacloprid).
Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. [7] [8] It is also used off-label to control sarcoptic mange and demodectic mange. [8] Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin ...
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