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[9] [6] Other side effects may include feeling lightheaded with standing due to changes in blood pressure, and angioedema. [9] Tamsulosin is an alpha blocker and works by relaxing muscles in the prostate. [10] Specifically it is an α 1-adrenergic receptor blocker. [6] Tamsulosin was approved for medical use in the United States in 1997. [6]
For instance, alpha blockers that are used for the reduction of blood pressure, such as phenoxybenzamine or phentolamine can have synergy with other drugs that affect smooth muscle, blood vessels, or drugs used for erectile dysfunction (i.e. sildenafil, tamsulosin, etc.).
Terazosin, tamsulosin and doxazosin are prime drug for BPH because they have a long half-life and modified release formulation. Tamsulosin is primarily used because it doesn't affect the blood pressure and the side effects of vasodilation is minimum. [44] [45] [2]
heart failure. The cardio-selective beta-1 blockers could cause adverse effects including bradycardia, reduced exercise ability, hypotension, atrioventricular nodal blockage and heart failure. [5] Other possible adverse effects include nausea and vomiting, abdominal discomfort, dizziness, weakness, headache, fatigue, and dryness in mouth and ...
This can lead to various adverse effects such as bronchospasm, tachycardia, arrhythmia, hypertension, and subcutaneous ischemia. [5] Other possible adverse effects include the Raynaud phenomenon, hypoglycaemia during exercise, muscle cramps, an increase in airway resistance and symptoms related to bradycardia. [11]
By reducing strain on the heart, this mechanism helps minimise the oxygen demand. Furthermore, calcium sensitizers provide an additional benefit. They open potassium channels in the heart muscle cells, resulting in vasodilation and improved blood flow. [53] This action reduces the workload on the heart.
Another word for muscle pain, myalgia affects muscles, ligaments, tendons, and connective tissues. In clinical trials of Cialis, one to four percent of men reported muscle pain as an adverse effect.
Uterus (when pregnant): this is minor compared to the relaxing effects of the β 2 receptor, agonists of which—notably albuterol/salbutamol—were formerly [citation needed] used to inhibit premature labor. Urethral sphincter; Bronchioles (although minor to the relaxing effect of β 2 receptor on bronchioles) Iris dilator muscle [4]