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Furosemide is mainly excreted by tubular secretion in the kidney. In kidney impairment, clearance is reduced, increasing the risk of adverse effects. [4] Lower initial doses are recommended in older patients (to minimize side effects) and high doses may be needed in kidney failure. [26]
Commonly prescribed drugs are prescribed according to guidelines around the world. For instance, for ischemic heart disease, the American College of Cardiology/American Heart Association (ACC/AHA) guideline is used in the United States and the European Society of Cardiology (ESC) guideline is used in Europe.
Deaths that have occurred from diflunisal usually involved mixed drugs and or extremely high dosage. The oral LD 50 is 500 mg/kg. Symptoms of overdose include coma, tachycardia, stupor, and vomiting. The lowest dose without the presence of other medicines which caused death was 15 grams.
RSV vaccine side effects in older adults . The CDC lists the following as possible side effects of the RSV vaccine: Pain, redness, and swelling where the shot is given. Fatigue. Fever. Headache ...
As you dive into your New Year’s resolutions, taking precautions to protect yourself from a quartet of infectious diseases can lessen your odds of starting off 2025 sick.
Norovirus cases are surging in the US, the CDC says. Here are the symptoms to look for, plus how long you're contagious for, per an infectious disease doctor.
Frailty can lead to increased risk of adverse side effects, complications, and mortality. [12] Older age by itself is not what defines frailty, it is however a syndrome found in older adults. Many adults over 65 are not living with frailty. [13] Frailty is not one specific disease, however is a combination of many factors.
Vitamin D supplements with or without calcium, while necessary for overall health, have no effect on preventing falls or fractures in older adults, according to a new draft recommendation from the ...