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Cimetidine, sold under the brand name Tagamet among others, is a histamine H 2 receptor antagonist that inhibits stomach acid production. [ 1 ] [ 9 ] [ 10 ] It is mainly used in the treatment of heartburn and peptic ulcers .
Notable drugs that experience a significant first pass effect are buprenorphine, chlorpromazine, cimetidine, diazepam, ethanol (drinking alcohol), imipramine, insulin, lidocaine, midazolam, morphine, pethidine, propranolol, and tetrahydrocannabinol (THC). First-pass metabolism is not to be confused with Phase I metabolism, which is a separate ...
Aminoglutethimide (AG), sold under the brand names Elipten, Cytadren, and Orimeten among others, is a medication which has been used in the treatment of seizures, Cushing's syndrome, breast cancer, and prostate cancer, among other indications.
Cimetidine was the first drug ever to reach more than $1 billion a year in sales, thus making it the first blockbuster drug. [26] In the pharmaceutical industry, a blockbuster drug is one that achieves acceptance by prescribing physicians as a therapeutic standard for, most commonly, a highly prevalent chronic (rather than acute) condition.
Anne was in nursing and health care administration. Before Patrick was born, she had even helped run a methadone clinic treating heroin addicts and later had worked in substance abuse and psychiatric wards for the Department of Veterans Affairs.
Methodology: For this study, GOBankingRates analyzed the most beautiful cities in the United States to find the places to retire with $250,000 in savings. First GOBankingRates found the most ...
Fecal occult blood testing (FOBT), as its name implies, aims to detect subtle blood loss in the gastrointestinal tract, anywhere from the mouth to the colon.Positive tests ("positive stool") may result from either upper gastrointestinal bleeding or lower gastrointestinal bleeding and warrant further investigation for peptic ulcers or a malignancy (such as colorectal cancer or gastric cancer).
A CFPB spokeswoman denied that political considerations influenced the timing of the lawsuits."When extensive, years-long CFPB investigations uncover wrongdoing, companies typically seek to ...