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Bile acid malabsorption (BAM), known also as bile acid diarrhea, is a cause of several gut-related problems, the main one being chronic diarrhea.It has also been called bile acid-induced diarrhea, cholerheic or choleretic enteropathy, bile salt diarrhea or bile salt malabsorption.
These conjugated bile acids are often referred to as bile salts. The pKa of the unconjugated bile acids are between 5 and 6.5, [ 4 ] and the pH of the duodenum ranges between 3 and 5, so when unconjugated bile acids are in the duodenum, they are almost always protonated (HA form), which makes them relatively insoluble in water.
Chronic diarrhea may be caused by excess bile salts entering the colon rather than being absorbed at the end of the small intestine (the ileum). This condition of bile acid malabsorption occurs after surgery to the ileum , in Crohn's disease , with a number of other gastrointestinal causes, or is commonly a primary, idiopathic condition.
Plus, high-fat foods cause the body to release bile salts and a hormone called cholecystokinin, which relaxes the lower esophageal sphincter, or LES, letting more acid wash up into the esophagus ...
GEM – initially called Government Employees Mutual Stores, and later Government Employees Mart before settling on G. E. M. Membership Department Stores, a profit-making company that was aimed at the governmental employees market; first store was opened in Denver in 1956; [190] after several expansions, the company filed for bankruptcy in 1974 ...
In the human liver, bile is composed of 97–98% water, 0.7% bile salts, 0.2% bilirubin, 0.51% fats (cholesterol, fatty acids, and lecithin), and 200 meq/L inorganic salts. [2] [3] The two main pigments of bile are bilirubin , which is orange-yellow, and its oxidised form biliverdin , which is green.
A bit of salt in the diet is necessary for good health. The seasoning is also a kitchen staple and taste booster, but Americans consume way too much — usually without even picking up a saltshaker.
The 1991 movie Career Opportunities was filmed at a Richway location converted into a Target store located at 4000 Covington Hwy. in Decatur, GA (location T378). That store closed in 1999, and moved five exits north on I-285 to La Vista Road. This former location now houses a church. Sunshine Market occupies a former Richway in West Palm Beach, FL.
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