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The chief and parietal cells produce and secrete mucus (F) to protect the lining of the stomach (C) against the harsh pH of stomach acid. The mucus is basic, while the stomach acid (A) is acidic. In the human digestive system, mucus is used as a lubricant for materials that must pass over membranes, e.g., food passing down the esophagus.
For decades, it was believed that the main function of the glands is to secrete alkaline (bicarbonate-containing) mucus in order to: [citation needed] protect the duodenum from the acidic content of chyme (which enters the duodenum from the stomach), provide an alkaline environment which promotes the activity of intestinal enzymes,
Pepsin is a protease that can digest and damage stomach cells. To prevent these disastrous effects, mucus and bicarbonate ions (HCO 3 −) are secreted by the foveolar cells. The mucus allows the acid at pH above 4 to penetrate lining, but below pH 4 (i.e. when acid is more concentrated) the acid cannot penetrate the mucus.
Alkaline mucus exists in the human eye, stomach, saliva, and cervix. [5] In the stomach, alkaline mucus is secreted by gastric glands in the gastric mucosa of the stomach wall. [6] Secretion of alkaline mucus is necessary to protect the mucous membrane of the stomach from acids released during digestion. [6]
She adds that these microbes provoke the intestinal cells to secrete mucus, which improves the mucosal barrier function. They also produce short chain fatty acids, which promote an anti ...
The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. [1] The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. [2] [3]
By loosening up the mucus, expectorants make your cough more productive—making it easier for you to cough up mucus effectively and clear your chest congestion.
The gastric mucosa is covered in surface mucous cells that produce the mucus necessary to protect the stomach's epithelial lining from gastric acid secreted by parietal cells in the glands, and from pepsin, a secreted digestive enzyme. Surface mucous cells follow the indentations and partly line the gastric pits.