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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    [4] [5] [6] PPIs are among the most widely sold medications in the world. The class of proton-pump inhibitor medications is on the World Health Organization's List of Essential Medicines. [7] [8] Omeprazole is the specific listed example. [7] [8]

  3. Pantoprazole - Wikipedia

    en.wikipedia.org/wiki/Pantoprazole

    [9] [5] The study of pantoprazole began in 1985, and it came into medical use in Germany in 1994. [10] It is available as a generic medication. [5] [11] In 2022, it was the sixteenth most commonly prescribed medication in the United States, with more than 30 million prescriptions.

  4. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Pantoprazole was first prepared in April 1985 by a small group of scale-up chemists. It is a dimethoxy-substituted pyridine bound to a fluoroalkoxy substituted benzimidazole. [5] Pantoprazole sodium is available as gastroresistant or delayed release tablets and as lyophilized powder for intravenous use.

  5. Cardiac output - Wikipedia

    en.wikipedia.org/wiki/Cardiac_output

    Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...

  6. Hypertrophic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Hypertrophic_cardiomyopathy

    Beta blockers are considered first-line agents, as they can slow down the heart rate and decrease the likelihood of ectopic beats. For people who cannot tolerate beta blockers, nondihydropyridine calcium channel blockers such as verapamil can be used, but are potentially harmful in people who also have low blood pressure or severe shortness of ...

  7. Cardiac glycoside - Wikipedia

    en.wikipedia.org/wiki/Cardiac_glycoside

    Cardiac glycosides have long served as the main medical treatment to congestive heart failure and cardiac arrhythmia, due to their effects of increasing the force of muscle contraction while reducing heart rate. Heart failure is characterized by an inability to pump enough blood to support the body, possibly due to a decrease in the volume of ...

  8. These Batch Cosmos Are Made to Serve a Crowd - AOL

    www.aol.com/batch-cosmos-made-serve-crowd...

    Yields: 4 servings. Prep Time: 5 mins. Total Time: 5 mins. Ingredients. 8 oz. citrus vodka. 4 oz. cranberry juice cocktail. 3 oz. fresh lime juice. 3 oz. triple sec ...

  9. Muscarinic acetylcholine receptor M2 - Wikipedia

    en.wikipedia.org/wiki/Muscarinic_acetylcholine...

    The muscarinic acetylcholine receptor M 2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. [5] Multiple alternatively spliced transcript variants have been described for this gene. [5] It is G i-coupled, reducing intracellular levels of cAMP.