Search results
Results from the WOW.Com Content Network
Graft and patient survival after transplantation have also improved over time, with 10 year graft survival rates for deceased donor transplants increasing from 42.3% in 1996–1999 to 53.6% in 2008-2011 and 10 year patient survival rate increasing from 60.5% in 1996–1999 to 66.9% in 2008–2011. [79]
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).
Organs regularly transplanted include lungs, heart, cornea, pancreas, and kidneys. Modes of donation are an altruistic living donation of a non-vital organ (generally a kidney) and post-mortal organ donation (PMOD). PMOD can be subdivided into donation after brain death (DBD) and donation after circulatory determination of death (DCDD). [5]
It is used when the kidneys are not working well, which is called kidney failure and includes acute kidney injury and chronic kidney disease. Renal replacement therapy includes dialysis (hemodialysis or peritoneal dialysis), hemofiltration, and hemodiafiltration, which are various ways of filtration of blood with or without machines.
The post-mortem interval (PMI) is the time that has elapsed since an individual's death. [1] When the time of death is not known, the interval may be estimated, and so an approximate time of death established. Postmortem interval estimations can range from hours, to days or even years depending on the type of evidence present. [2]
Overall postoperative complications after kidney transplantation occur in approximately 12% to 25% of kidney transplant patients. [ 34 ] Following a transplant, recipients will be given lab draws , ultrasounds , and other tests to see if the transplanted organ is being accepted .
Chronic kidney disease results in worse all-cause mortality (the overall death rate) which increases as kidney function decreases. [90] The leading cause of death in chronic kidney disease is cardiovascular disease, regardless of whether there is progression to stage 5. [90] [91] [92]
The above formula only applies for GFR calculation when it is equal to the clearance rate. The normal range of GFR, adjusted for body surface area , is 100–130 average 125 (mL/min)/(1.73 m 2 ) in men and 90–120 (mL/min)/(1.73 m 2 ) in women younger than the age of 40.