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  2. Koch's postulates - Wikipedia

    en.wikipedia.org/wiki/Koch's_postulates

    Robert Hermann Koch (11 December 1843 – 27 May 1910) was a German physician who developed Koch's postulates. [1] Koch's postulates (/ k ɒ x / KOKH) [2] are four criteria designed to establish a causal relationship between a microbe and a disease. The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884, based on earlier ...

  3. Molecular Koch's postulates - Wikipedia

    en.wikipedia.org/wiki/Molecular_Koch's_postulates

    Molecular Koch's postulates are a set of experimental criteria that must be satisfied to show that a gene found in a pathogenic microorganism encodes a product that contributes to the disease caused by the pathogen. Genes that satisfy molecular Koch's postulates are often referred to as virulence factors.

  4. Microbial pathogenesis - Wikipedia

    en.wikipedia.org/wiki/Microbial_pathogenesis

    In 1996, Fredricks and Relman suggested the following postulates for the novel field of microbial pathogenesis. [2] [3](i) A nucleic acid sequence belonging to a putative pathogen should be present in most cases of an infectious disease.

  5. Koch–Pasteur rivalry - Wikipedia

    en.wikipedia.org/wiki/Koch–Pasteur_rivalry

    Koch had transformed bacteriology by introducing the technique of pure culture, whereby he established the microbial cause of the disease anthrax (1876), had introduced both staining and solid culture plates to bacteriology (1881), had identified the microbial cause of tuberculosis (1882), had incidentally popularized Koch's postulates for ...

  6. Koch reaction - Wikipedia

    en.wikipedia.org/wiki/Koch_reaction

    The Koch reaction is an organic reaction for the synthesis of tertiary carboxylic acids from alcohols or alkenes and carbon monoxide. Some commonly industrially produced Koch acids include pivalic acid , 2,2-dimethylbutyric acid and 2,2-dimethylpentanoic acid. [ 1 ]

  7. Stanley Falkow - Wikipedia

    en.wikipedia.org/wiki/Stanley_Falkow

    He formulated molecular Koch's postulates, which have guided the study of the microbial determinants of infectious diseases since the late 1980s. [2] Falkow spent over 50 years uncovering molecular mechanisms of how bacteria cause disease and how to disarm them. [ 1 ]

  8. Microorganism - Wikipedia

    en.wikipedia.org/wiki/Microorganism

    Based on these experiments, he devised criteria for establishing a causal link between a microorganism and a disease and these are now known as Koch's postulates. [18] Although these postulates cannot be applied in all cases, they do retain historical importance to the development of scientific thought and are still being used today. [19]

  9. Medical microbiology - Wikipedia

    en.wikipedia.org/wiki/Medical_microbiology

    He developed a series of criteria around this that have become known as the Koch's postulates. [7] A major milestone in medical microbiology is the Gram stain. In 1884 Hans Christian Gram developed the method of staining bacteria to make them more visible and differentiated under a microscope. This technique is widely used today. [8]

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