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One survey in Ontario found that 25% currently or formerly obtained DIY hormones, whereas for trans people of color living in San Francisco a different survey found that 63% had relied on DIY. [ 1 ] [ 3 ] According to a 2022 review, at the low end, 11% of Ontarian transgender people report having used DIY HRT; at the other extreme, 79% of trans ...
[15] [13] [14] Estradiol valerate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [5] [4] [16] It is an estrogen ester and a prodrug of estradiol in the body. [16] [5] [4] Because of this, it is considered to be a natural and bioidentical form of estrogen. [16] [17] [4] [18]
Feminizing hormone therapy, also known as transfeminine hormone therapy, is a form of gender-affirming care and a gender-affirming hormone therapy to change the secondary sex characteristics of transgender people from masculine to feminine.
It is likely the case that pre-oophorectomy, residual estrogen production is protective. However, after oophorectomy, some trans men may have insufficient estrogen to slow bone loss. Pre-clinical research has suggested the importance of low-dose estrogen supplementation for those beginning cross-sex hormone therapy (XHT) during adolescence. [48]
Gender-affirming hormone therapy (GAHT), also called hormone replacement therapy (HRT) or transgender hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.
Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins. [7] [8] In the past, EE was widely used for various indications such as the treatment of menopausal symptoms, gynecological disorders, and certain hormone-sensitive cancers.
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