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Spondyloarthritis (SpA), also known as spondyloarthropathy, is a collection of clinical syndromes that are connected by genetic predisposition and clinical manifestations. [1] The best-known clinical subtypes are enteropathic arthritis (EA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and reactive arthritis (ReA). [ 2 ]
About one third of those with ankylosing spondylitis have severe disease, which reduces life expectancy. [52] As increased mortality in ankylosing spondylitis is related to disease severity, factors negatively affecting outcomes include: [50] [53] Male sex [54] Plus three of the following in the first two years of disease:
Axial spondyloarthritis (also often referred to as axSpA) is a chronic, immune-mediated disease predominantly affecting the axial skeleton (sacroiliac joints and spine). [1] The term itself is an umbrella term characterizing a diverse disease family united by shared clinical and genetic features, such as the involvement of the axial skeleton. [ 2 ]
This drug results in rapid relief of symptoms and improved quality of life by reducing pain, stiffness, and disease progression, according to a 2024 study in Cureus. It was difficult for Steff to ...
It is classified as a type of seronegative spondyloarthropathy. Genetics are thought to be strongly involved in the development of psoriatic arthritis. [3] Obesity and certain forms of psoriasis are thought to increase the risk. [3] Psoriatic arthritis affects up to 30% of people with psoriasis and occurs in both children and adults. [3]
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Seronegative spondyloarthropathy: Psoriatic arthritis; Ankylosing spondylitis; Rheumatoid arthritis: Felty's syndrome; Juvenile idiopathic arthritis; Adult-onset Still's disease; Crystal arthropathy; Gout; Chondrocalcinosis; Osteoarthritis; Hemarthrosis (joint bleeding) Synovitis is the medical term for inflammation of the synovial membrane ...
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