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Spondyloarthritis (SpA), also known as spondyloarthropathy, is a collection of clinical syndromes that are connected by genetic predisposition and clinical manifestations. [1] The best-known clinical subtypes are enteropathic arthritis (EA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and reactive arthritis (ReA). [ 2 ]
About one third of those with ankylosing spondylitis have severe disease, which reduces life expectancy. [52] As increased mortality in ankylosing spondylitis is related to disease severity, factors negatively affecting outcomes include: [50] [53] Male sex [54] Plus three of the following in the first two years of disease:
Axial spondyloarthritis (also often referred to as axSpA) is a chronic, immune-mediated disease predominantly affecting the axial skeleton (sacroiliac joints and spine). [1] The term itself is an umbrella term characterizing a diverse disease family united by shared clinical and genetic features, such as the involvement of the axial skeleton. [ 2 ]
Along with reactive arthritis, psoriatic arthritis, and idiopathic ankylosing spondylitis, this type of arthritis is categorized as a seronegative spondyloarthropathy. [4] Other gastrointestinal disorders like Whipple's disease, celiac disease, and intestinal bypass surgery for severe obesity can also cause joint involvement. The pathogenesis ...
The Living to 100 Life Expectancy Calculator gave me a surprisingly precise prediction: "You're going to live for 27 more years!" But it suggested I might add three months to my life if I cut down ...
It is classified as a type of seronegative spondyloarthropathy. Genetics are thought to be strongly involved in the development of psoriatic arthritis. [3] Obesity and certain forms of psoriasis are thought to increase the risk. [3] Psoriatic arthritis affects up to 30% of people with psoriasis and occurs in both children and adults. [3]
Life expectancy in the U.S. is projected to increase from 78.3 years in 2022 to 79.9 years in 2035 and to 80.4 years in 2050 for all sexes combined, researchers said.
Seronegative spondyloarthropathy: Psoriatic arthritis; Ankylosing spondylitis; Rheumatoid arthritis: Felty's syndrome; Juvenile idiopathic arthritis; Adult-onset Still's disease; Crystal arthropathy; Gout; Chondrocalcinosis; Osteoarthritis; Hemarthrosis (joint bleeding) Synovitis is the medical term for inflammation of the synovial membrane ...