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For moderate-to-severe plaque psoriasis, phototherapy is an efficient first-line treatment that reduces inflammation by promoting keratinocyte apoptosis, suppressing keratinocyte proliferation, and reducing the activity of the Th1 and Th17 inflammatory pathways. [26]
Psoriasis vulgaris (also known as chronic stationary psoriasis or plaque-like psoriasis) is the most common form and affects 85–90% of people with psoriasis. [12] Plaque psoriasis typically appears as raised areas of inflamed skin covered with silvery-white, scaly skin. These areas are called plaques and are most commonly found on the elbows ...
Deucravacitinib, sold under the brand name Sotyktu, is a medication used for the treatment of moderate-to-severe plaque psoriasis. [7] It is a tyrosine kinase 2 (TYK2) inhibitor and it is taken by mouth. [7] It was developed by Bristol Myers Squibb. [10]
Brodalumab, sold under the brand name Siliq in the US and Kyntheum in the EU, is a human monoclonal antibody designed for the treatment of inflammatory diseases. [3] [4] [5]In February 2017, it received US FDA approval to treat moderate to severe plaque psoriasis in people who have not improved with other treatments.
Risankizumab was approved by the U.S. Food and Drug Administration (FDA) for treatment of moderate-to-severe plaque psoriasis in April 2019. [13] [10] [14]The FDA approved risankizumab based on evidence primarily from five clinical trials (Trial 1/NCT02684370, Trial 2/NCT02684357, Trial 3/NCT02672852, Trial 4/ NCT02694523, and Trial 5/NCT02054481) of 1606 participants with moderate to severe ...
It is approved for the treatment of adults with moderate-to-severe plaque psoriasis in the United States and in the European Union. [2] [3] [5] Tildrakizumab was designed to block interleukin-23 (IL-23), a cytokine that plays a key role in managing the immune system and autoimmune disease. [6] [7]
ICD-10 is the 10th revision of the International Classification of Diseases (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. [1]
Psoriasis is a common, chronic, and recurrent inflammatory disease of the skin characterized by circumscribed, erythematous, dry, scaling plaques. [97] [98] [99] Psoriasis vulgaris. Annular pustular psoriasis; Drug-induced psoriasis; Exanthematic pustular psoriasis; Generalized pustular psoriasis (pustular psoriasis of von Zumbusch)