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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  3. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    At the same time, loop diuretics inhibit the tubuloglomerular feedback mechanism so that increase in salts at the lumen near macula densa does not trigger a response that reduces the GFR. [6] Loop diuretics also inhibit magnesium and calcium reabsorption in the thick ascending limb. Absorption of magnesium and calcium are dependent upon the ...

  4. Chlortalidone - Wikipedia

    en.wikipedia.org/wiki/Chlortalidone

    Chlortalidone is considered a first-line medication for treatment of high blood pressure. [2] Some recommend chlortalidone over hydrochlorothiazide. [1] [15] A meta-analysis of randomized controlled trials found that chlortalidone is more effective than hydrochlorothiazide for lowering blood pressure, while the two drugs have similar toxicity.

  5. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    Metolazone and a loop diuretic will synergistically enhance diuresis over the use of either agent alone. Using this combination, diuretic effects will occur at two different segments of the nephron; namely, the loop diuretic will act at the loop of Henle, and metolazone will act at the distal convoluted tubule. Metolazone is frequently ...

  6. Sake made in space could sell for $500,000 a glass - AOL

    www.aol.com/news/sake-made-space-could-sell...

    Bottles of Dassai 23 sake are seen at Asahi Shuzo Co's facility in Iwakuni, Yamaguchi Prefecture, Japan, on July 7, 2022. (Noriko Hayashi/Bloomberg/Getty Images)

  7. Hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Hydrochlorothiazide

    Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]

  8. Zepbound Weight Loss Medication Approved by FDA to Treat ...

    www.aol.com/fda-approves-weight-loss-medication...

    The weight loss drug Zepbound, generically known as tirzepatide, is also now an approved medication to treat obstructive sleep apnea, per a Food and Drug Administration Dec. 20 press release. The ...

  9. Transgender volleyball controversy: Judge rules San Jose ...

    www.aol.com/sports/transgender-volleyball...

    A federal judge denied emergency injunctive relief despite complaints from competitors who object to the Spartans player's participation on the grounds that she is transgender.