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Losartan is generally marketed as the (basic) potassium salt of the aromatized negatively charged tetrazole, called "losartan potassium". [12] The molecule has an extended biphenyl group with a tetrazole which is being used in place of the carboxylic acid as a bioisostere .
Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [1] [2] It consists of losartan, an angiotensin II receptor blocker; and hydrochlorothiazide, a thiazide diuretic. [1] [2] It is taken by mouth. [1] [2]
Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...
Scammers are using AI-powered voice-cloning tools to prey on people. But experts say there's a simple way to protect you and your family.
Humans and felines may not communicate in the same ways, but we can understand one another all the same. Many of our body language signals are similar, after all, and there are many universal ...
Gout may be worsened by thiazide diuretics, while losartan reduces serum urate. [64] Kidney stones may be improved with the use of thiazide-type diuretics [65] Heart block. β-blockers and nondihydropyridine calcium channel blockers should not be used in patients with heart block greater than first degree. JNC8 does not recommend β-blockers as ...
Use disposable paper towels, rather than reusable rags, when cleaning a contaminated surface. Clothes or bedding used by someone with norovirus should be handled with gloves and washed with ...
Losartan, valsartan, candesartan, irbesartan, telmisartan and olmesartan all contain a biphenyl-methyl group. Losartan is partly metabolized to its 5- carboxylic acid metabolite EXP 3174, which is a more potent AT 1 receptor antagonist than its parent compound [ 17 ] and has been a model for the continuing development of several other ARBs.