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  2. Silent mutation - Wikipedia

    en.wikipedia.org/wiki/Silent_mutation

    Silent mutations, also called synonymous or samesense mutations, are mutations in DNA that do not have an observable effect on the organism's phenotype. The phrase silent mutation is often used interchangeably with the phrase synonymous mutation ; however, synonymous mutations are not always silent, nor vice versa.

  3. Synonymous substitution - Wikipedia

    en.wikipedia.org/wiki/Synonymous_substitution

    Point substitution mutations of a codon, classified by their impact on protein sequence. A synonymous substitution (often called a silent substitution though they are not always silent) is the evolutionary substitution of one base for another in an exon of a gene coding for a protein, such that the produced amino acid sequence is not modified.

  4. Phenotype - Wikipedia

    en.wikipedia.org/wiki/Phenotype

    For example, silent mutations that do not change the corresponding amino acid sequence of a gene may change the frequency of guanine-cytosine base pairs . These base pairs have a higher thermal stability ( melting point ) than adenine - thymine , a property that might convey, among organisms living in high-temperature environments, a selective ...

  5. List of genetic disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_genetic_disorders

    The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child. There are over 6,000 known genetic disorders in humans.

  6. Category:Mutation - Wikipedia

    en.wikipedia.org/wiki/Category:Mutation

    Mutations are permanent, transmissible changes to the genetic material (usually DNA or RNA) ... Silent mutation; Single-nucleotide polymorphism; Slipped strand ...

  7. Missense mutation - Wikipedia

    en.wikipedia.org/wiki/Missense_mutation

    In genetics, a missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid. [1] It is a type of nonsynonymous substitution . Substitution of protein from DNA mutations

  8. Muller's morphs - Wikipedia

    en.wikipedia.org/wiki/Muller's_morphs

    Hermann J. Muller (1890–1967), who was a 1946 Nobel Prize winner, coined the terms amorph, hypomorph, hypermorph, antimorph and neomorph to classify mutations based on their behaviour in various genetic situations, as well as gene interaction between themselves. [1] These classifications are still widely used in Drosophila genetics to ...

  9. Mutationism - Wikipedia

    en.wikipedia.org/wiki/Mutationism

    [c] [20] [21] By this, de Vries meant that a new form of the plant was created in a single step (not the same as a mutation in the modern sense); no long period of natural selection was required for speciation, and nor was reproductive isolation. [22] In the view of the historian of science Peter J. Bowler, De Vries used the term to mean [1]