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  2. Ertugliflozin - Wikipedia

    en.wikipedia.org/wiki/Ertugliflozin

    Ertugliflozin, sold under the brand name Steglatro, is a medication used for the treatment of type 2 diabetes. [ 3 ] [ 4 ] The most common side effects include fungal infections of the vagina and other infections of the female reproductive system.

  3. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    The 2022 American Diabetes Association (ADA) standards of medical care in diabetes include SGLT2 inhibitors as a first line pharmacological therapy for type 2 diabetes (usually together with metformin), specifically in patients with chronic kidney disease, cardiovascular disease or heart failure.

  4. Merck's Steglatro Non-Inferior in Cardiovascular ... - AOL

    www.aol.com/news/mercks-steglatro-non-inferior...

    Merck's (MRK) type 2 diabetes drug, Steglatro, achieves primary endpoint of non-inferiority in major adverse CV events compared to placebo in a late-stage cardiovascular outcomes study.

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  6. Thiazolidinedione - Wikipedia

    en.wikipedia.org/wiki/Thiazolidinedione

    Thiazolidinedione ligand dependent transactivation is responsible for the majority of anti-diabetic effects. The activated PPAR/RXR heterodimer binds to peroxisome proliferator hormone response elements upstream of target genes in complex with a number of coactivators such as nuclear receptor coactivator 1 and CREB binding protein, this causes upregulation of genes (for a full list see PPARγ):

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    You've Got Mail!® Millions of people around the world use AOL Mail, and there are times you'll have questions about using it or want to learn more about its features. That's why AOL Mail Help is here with articles, FAQs, tutorials, our AOL virtual chat assistant and live agent support options to get your questions answered.

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