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Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. [3]
Hydroxychloroquine has also been linked to serious side effects, including cardiac arrest, heart rhythm issues, liver failure, and kidney disorders, as noted by a 2020 FDA warning about the drug's ...
Der has made contributions to the fields of molecular pharmacology and cancer cell biology. One early discovery was the presence of activated Ras oncogenes in human cancers in 1982, marking the identification of the very first cancer genes. [3] RAS genes comprise the most frequently mutated oncogene family in human cancers.
A World Health Organization infographic that states that hydroxychloroquine does not prevent illness or death from COVID-19. Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [54] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [55]
Brett Giroir, who handles the Trump administration’s coronavirus testing, said there is no evidence that the drug is an “effective” treatment for COVID-19.
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A World Health Organization infographic that states that hydroxychloroquine does not prevent illness or death from COVID-19. Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [1] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [2]
TMPRSS2-ERG fusion gene is the most frequent, present in 40% - 80% of prostate cancers in humans. ERG overexpression contributes to development of androgen-independence in prostate cancer through disruption of androgen receptor signaling. [17]